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Symbol
Name
ID

Kdm6a
lysine (K)-specific demethylase 6A
MGI:1095419

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Acute lymphoblastic leukemia	T-cell acute lymphoblastic leukemias	Autoimmune thrombocytopenia	Subacute progressive viral hepatitis	Recurrent otitis media	Abnormality of immune system physiology	Recurrent aspiration pneumonia	Recurrent infections
Disease(s) Associated with KDM6A	Acute lymphoblastic leukemia	T-cell acute lymphoblastic leukemias	Autoimmune thrombocytopenia	Subacute progressive viral hepatitis	Recurrent otitis media	Abnormality of immune system physiology	Recurrent aspiration pneumonia	Recurrent infections
acute lymphoblastic leukemia
hepatocellular carcinoma
Kabuki syndrome

Mouse Phenotypes		enlarged spleen	increased spleen weight	abnormal granulocyte morphology	increased neutrophil cell number	increased granulocyte number	increased B cell number	increased monocyte cell number	decreased leukocyte cell number
Availability	Mouse Genotype	enlarged spleen	increased spleen weight	abnormal granulocyte morphology	increased neutrophil cell number	increased granulocyte number	increased B cell number	increased monocyte cell number	decreased leukocyte cell number
	Kdm6a^tm1.1Afst/Kdm6a^tm1.1Afst Gt(ROSA)26Sor^{tm9(cre/ESR1)Arte}/Gt(ROSA)26Sor⁺ (conditional)
	Kdm6a^tm1Cdcn/Kdm6a^tm1Cdcn Tg(CAG-cre/Esr1*)5Amc/0 (conditional)
	Kdm6a^tm1Cdcn/Y Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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